Table 1 Primers used for qRT-PCR

Cathepsin B

NM_022597.2

FP: CCCTGTGAACACCATGTCAATG

RP: GATGTGGAGTAGCCAGCCTCAC

Cathepsin K

NM_031560.2

FP: TGTGGGTGTTCAAGTTTTTGCTG

RP: GTACTGCTTCCCGTGGGTCTTC

Cathepsin L1

NM_013156.1

FP: ACCATGACCCCTTTACTCCTCCT

RP: CTCCTCCACTCTTCCTCATTCGT

Cathepsin S

NM_017320.1

FP: CCATTCCTCCTTCTTCCTCTACCA

RP: CCATCAAGAGTCCCATAGCCAAC

Heparanase

NM_022605.1

FP: GACGGACTGCTTTCCAAATCC

RP: CGGGGAGAGGTTTTTCTGTTAGAG

HPRT1

XM_343829

FP: CAGTACAGCCCCAAAATGGT

RP: CAAGGGCATATCCAACAACA

MMP2

NM_031054.2

FP: TCTCCCCCAAAACAGACAAAGAG

RP: TCCTTCAGCACAAAGAGGTTGC

MMP9

NM_031055

FP: CTGCCTGCACCACTAAAGG

RP: GAAGACGAAGGGGAAGACG

MMP12

NM_053963

FP: CTGGGCAACTGGACACCT

RP: CTACATCCGCACGCTTCA

MMP14

NM_031056.1

FP: GTTCTGGCGGGTGAGGAATAAC

RP: TCATAGGCAGTGTTGATGGATGC

TIMP-1

NM_053819

FP: GGTTCCCCAGAAATCATCG

RP: GGAAACCTGTGGCATTTCC