Figure 1From: Mice with different susceptibility to tick-borne encephalitis virus infection show selective neutralizing antibody response and inflammatory reaction in the central nervous system Chromosomal composition of the mouse strains used in this study based on precise chromosomal mapping. The RC strain CcS-11 contains a random set of ~12.5% genes from strain STS donor strain and 87.5% genes from strain BALB/c (background strain). Sex chromosomes are not shown in this figure (A). Survival of mice after s.c. inoculation of TBEV. Mice (n = 10 per group) were inoculated with 103 pfu of TBEV and observed for lethality (B). Survival of mice (BALB/c, n = 8; CcS-11, n = 9; STS, n = 7) after i.c. inoculation of 10 pfu of TBEV (C).Back to article page