Figure 7
From: Primary blast injury-induced lesions in the retina of adult rats
Expression and distribution of AQP4 (green) and GFAP (red) in the retina of sham (A-C) and BL rats (D-L). In the sham retina, AQP4 expression is localized in the blood vessels (asterisk), Müller cells, and GFAP-labeled astrocytes (single arrow) (A-C). Following blast exposure, AQP4 expression is markedly increased in various retinal layers at different time points (24 and 72 h, D-I). Intense AQP4 immunoreactivity is localized in GFAP-labeled astrocytes and blood vessels. It is also markedly enhanced in the Müller cell process in parallel arrays (D-I). At 2 weeks, AQP4 immunoreactivity is reduced to levels almost comparable to that of the sham (J-L). AQ4 immunoreactivity remains intense in the blood vessels (asterisk) at all time-points. Scale bar=20 μm (A-L).