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Figure 7 | Journal of Neuroinflammation

Figure 7

From: M-CSF increases proliferation and phagocytosis while modulating receptor and transcription factor expression in adult human microglia

Figure 7

Macrophage colony-stimulating factor (M-CSF) increases adult human microglial expression of C/EBP β . (A-C) C/EBPβ is expressed by PU.1-immunopositive adult human microglia in mixed glial cultures. (D-F) M-CSF increases the intensity of C/EBPβ labeling in adult human microglia and the number of microglia which express C/EBPβ. (G) Quantification of microglial C/EBPβ expression showing that M-CSF increases the percentage of microglia which express C/EBPβ. P < 0.001, n = 12. Scale bar = 100 μm.

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Journal of Neuroinflammation

ISSN: 1742-2094