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Figure 8 | Journal of Neuroinflammation

Figure 8

From: M-CSF increases proliferation and phagocytosis while modulating receptor and transcription factor expression in adult human microglia

Figure 8

Macrophage colony-stimulating factor (M-CSF) increases adult human microglial expression of DAP12. (A) DAP12 monocyte/microglial adaptor protein is expressed by human microglia isolated from biopsy tissue. (B) Treatment of microglia with M-CSF increases their expression of DAP12 as seen by increased intensity of immunochemical staining. (C) Quantification of DAP12 staining intensity shows a significant increase in DAP12 expression with M-CSF treatment. P < 0.0001, n = 8. Scale bar = 100 μm.

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Journal of Neuroinflammation

ISSN: 1742-2094