Figure 6
From: Inhibition of astroglial NF-kappaB enhances oligodendrogenesis following spinal cord injury
TNFR2 expression is increased in the IκBα-dn injured spinal cord compared to wild-type 6 weeks post-spinal cord injury. (A) Quantification of TNFR2 protein expression levels in the injured spinal cord of wild-type (WT) and IκBα-dn mice showing significantly less protein in WT mice 6 weeks after spinal cord injury (SCI) compared to IκBα-dn mice. Each bar represents the mean ± SEM. *P < 0.05. N = 3 to 4 animals per group. (B) Representative confocal images of mature CC1 oligodendrocytes and TNFR2 expression in naïve and injured spinal cord from WT and IκBα-dn mice, showing that a subset of TNFR2+ cells co-localizes with CC1+ oligodendrocytes.