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Figure 1 | Journal of Neuroinflammation

Figure 1

From: Chronic oral administration of minocycline to sheep with ovine CLN6 neuronal ceroid lipofuscinosis maintains pharmacological concentrations in the brain but does not suppress neuroinflammation or disease progression

Figure 1

High-performance liquid chromatography of minocycline. High-performance liquid chromatography elution of minocycline extracted from plasma (A) and cerebrospinal fluid (B) taken from the same animal after chronic treatment with minocycline at 25/kg/day. The minocycline peak eluted consistently between 8.2 and 8.3 min. Scanning this peak from 250 to 450 nm yielded a single absorbance peak at 355 nm (C).

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Journal of Neuroinflammation

ISSN: 1742-2094