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Figure 2 | Journal of Neuroinflammation

Figure 2

From: T-cell reconstitution during murine acquired immunodeficiency syndrome (MAIDS) produces neuroinflammation and mortality in animals harboring opportunistic viral brain infection

Figure 2

Elevated levels of programmed death-1 on T-lymphocytes during chronic retroviral infection. C57BL/6 mice were infected with LP-BM5 and monitored for the expression of programmed death-1 (PD-1) on circulating CD4+ and CD8+ T-cells at the indicated time points. Peripheral blood mononuclear cell preparations from individual animals were stained with CD3- allophycocyanin (APC)-Cy7, CD4-eFlour450, CD8-PE-Cy7 and PD-1- fluorescein isothiocyanate (FITC) for flow cytometric analysis. Representative histograms showing the percentage of PD-1 expression on CD4+ or CD8+ T-cells at the indicated time points are presented.

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Journal of Neuroinflammation

ISSN: 1742-2094