Table 2 Assay performance
Analyte | Plasma | CSF | ||
|---|---|---|---|---|
Sensitivity (pg/mL) | Inter-assay CV range (QC concentration range) | Sensitivity (pg/mL) | Inter-assay CV range (QC concentration range) | |
IL-1Ra | 16 | 8.2 to 3.2 (360 to 10,009 pg/mL) | Same assay as for plasma | |
IL-1α | 6.1 | 9.0 to 4.2 (25 to 366 pg/mL) | 4.75 | 6.6 to 9.2 (20 to 800 pg/mL) |
IL-1β | 1.3 | 10.3 to 6.3 (17.5 to 146 pg/mL) | 0.48 | 30.3 to 10.9 (1.3 to 10.9 pg/mL) |
IL-6 | 1.7 | 5.9 to 2 (41 to 322 pg/mL) | 17 | 7.1 to 2.6 (213 to 1,229 pg/mL) |
IL-8 | 4.7 | 7.9 to 16 (109 to 975 pg/mL) | 17 | 8.9 to 15.8 (185 to 9,152 pg/mL) |
IL-10 | 1.3 | 10.3 to 6.26 (7.5 to 146 pg/mL) | 0.82 | 10.6 to 5.5 (5.16 to 232 pg/mL) |
MCP-1 | 45 | 19.5 to 11.3 (207 to 1,759 pg/mL) | 147 | (19 to 6.5 (9,303 to 11,275 pg/mL) |
TNF-α | 0.35 | 6.7 to 7.0 (16.8 to 159 pg/mL) | 2.5 | 25 to 15.8 (4.3 to 28.1 pg/mL) |
CRP | 350 | 14.8 to 1 (9.2 to 97 mg/L) | ND | |