Table 5 Allele and genotype distribution of the five selected SNPs in male cerebral palsy cases and controls
From: The association between sex-related interleukin-6 gene polymorphisms and the risk for cerebral palsy
| Â | Group | Allele frequency | P value | Genotype frequency | P value | Hardy-Weinberg equilibrium | |||
|---|---|---|---|---|---|---|---|---|---|
rs1800796 | Â | C | G | Â | C/C | C/G | G/G | Â | Â |
Case | 678 (0.690) | 304 (0.310) | 0.092 | 242 (0.493) | 194 (0.395) | 55 (0.112) | 0.113 | 0.093 | |
Control | 631 (0.655) | 333 (0.345) | 206 (0.427) | 219 (0.454) | 57 (0.118) | 0.917 | |||
rs2069837 | Â | A | G | Â | A/A | A/G | G/G | Â | Â |
Case | 790 (0.808) | 188 (0.192) | 0.009 a | 326 (0.667) | 138 (0.282) | 25 (0.051) | 0.041 | 0.044 | |
Control | 718 (0.759) | 228 (0.241) | 279 (0.590) | 160 (0.338) | 34 (0.072) | 0.101 | |||
rs2066992 | Â | G | T | Â | G/G | G/T | T/T | Â | Â |
Case | 303 (0.309) | 677 (0.691) | 0.119 | 53 (0.108) | 197 (0.402) | 240 (0.490) | 0.159 | 0.193 | |
Control | 330 (0.342) | 634 (0.658) | 55 (0.114) | 220 (0.456) | 207 (0.429) | 0.764 | |||
rs2069840 | Â | C | G | Â | C/C | C/G | G/G | Â | Â |
Case | 901 (0.914) | 85 (0.086) | 0.646 | 411 (0.834) | 79 (0.160) | 3 (0.006) | 0.742 | 0.704 | |
Control | 877 (0.908) | 89 (0.092) | 396 (0.820) | 85 (0.176) | 2 (0.004) | 0.253 | |||
rs10242595 | Â | A | G | Â | A/A | A/G | G/G | Â | Â |
Case | 870 (0.895) | 102 (0.105) | 0.304 | 391 (0.805) | 88 (0.181) | 7 (0.014) | 0.578 | 0.426 | |
Control | 838 (0.880) | 114 (0.120) | 372 (0.782) | 94 (0.197) | 10 (0.021) | 0.168 | |||