Table 8 Allele and genotype distributions of the SNPs in male cerebral palsy (CP) patients with or without periventricular leukomalacia (PVL)
From: The association between sex-related interleukin-6 gene polymorphisms and the risk for cerebral palsy
| Â | Group | Allele frequency | P value | Genotype frequency | P value | Hardy-Weinberg equilibrium | |||
|---|---|---|---|---|---|---|---|---|---|
rs1800796 | Â | C | G | Â | C/C | C/G | G/G | Â | Â |
CP + PVL | 80 (0.714) | 32 (0.286) | 0.206 | 33 (0.589) | 14 (0.250) | 9 (0.161) | 0.014 b | 0.004 | |
CP − PVL | 598 (0.687) | 272 (0.331) | 0.136 | 209 (0.480) | 180 (0.414) | 46 (0.106) | 0.272 | 0.437 | |
| Â | Control | 631 (0.655) | 333 (0.345) | Â | 206 (0.427) | 219 (0.454) | 57 (0.118) | Â | 0.917 |
rs2069837 | Â | A | G | Â | A/A | A/G | G/G | Â | Â |
CP + PVL | 91 (0.812) | 21 (0.188) | 0.207 | 39 (0.696) | 13 (0.232) | 4 (0.071) | 0.263 | 0.075 | |
CP − PVL | 699 (0.807) | 167 (0.193) | 0.013 a | 287 (0.663) | 125 (0.289) | 21 (0.048) | 0.057 | 0.131 | |
| Â | Control | 718 (0.759) | 228 (0.241) | Â | 279 (0.590) | 160 (0.338) | 34 (0.072) | Â | 0.101 |
rs2066992 | Â | G | T | Â | G/G | G/T | T/T | Â | Â |
CP + PVL | 32 (0.286) | 80 (0.714) | 0.230 | 9 (0.161) | 14 (0.250) | 33 (0.589) | 0.013 c | 0.004 | |
CP − PVL | 271 (0.312) | 597 (0.688) | 0.171 | 44 (0.101) | 183 (0.422) | 207 (0.477) | 0.348 | 0.705 | |
| Â | Control | 330 (0.342) | 634 (0.658) | Â | 55 (0.114) | 220 (0.456) | 207 (0.429) | Â | 0.764 |
rs2069840 | Â | C | G | Â | C/C | C/G | G/G | Â | Â |
CP + PVL | 105 (0.938) | 7 (0.062) | 0.554 | 49 (0.875) | 7 (0.125) | 0 (0.000) | 0.554 | 0.618 | |
CP − PVL | 796 (0.911) | 78 (0.890) | 0.830 | 362 (0.828) | 72 (0.165) | 3 (0.007) | 0.778 | 0.777 | |
| Â | Control | 877 (0.908) | 89 (0.092) | Â | 396 (0.820) | 85 (0.176) | 2 (0.004) | Â | 0.253 |
rs10242595 | Â | A | G | Â | A/A | A/G | G/G | Â | Â |
CP + PVL | 99 (0.900) | 11 (0.100) | 0.543 | 45 (0.818) | 9 (0.164) | 1 (0.018) | 0.821 | 0.500 | |
CP − PVL | 771 (0.894) | 91 (0.106) | 0.341 | 346 (0.803) | 79 (0.183) | 6 (0.014) | 0.603 | 0.542 | |
| Â | Control | 838 (0.880) | 114 (0.120) | Â | 372 (0.782) | 94 (0.197) | 10 (0.021) | Â | 0.168 |