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Table 1 Baseline characteristics of the untreated and treated LNB patients and of the borrelia antibody negative patients

From: CXCL13 and neopterin concentrations in cerebrospinal fluid of patients with Lyme neuroborreliosis and other diseases that cause neuroinflammation

     Antibodies        Presenting symptom
Group No Age, years (Median, range) Sex (F/M) B31a(pos/neg) C6b(pos/neg) IT-indexc(pos/neg/ND) Cells/μld(Median, range) OC-bandse(pos/neg) Protein (mg/ml) (Median, range) Duration of symptomsf(days) (Median, range) Tick biteg(No of patients) EMh(No of patients) FPi Radiculits/Radiating pain
Untreated LNB 38 66 (3–80) 16/22 37/1 37/1 29/3/6 104 (0–1516) 21/4 1034 (454–3148) 30 (0–120) 11 2 19 30
Treated LNB 24 64 (34–79) 8/16 22/2 18/6 19/4/1 35 (0–120) 10/0 601 (267–1597) NAj NA NA NA NA
Non-LNB 239 50 (1–91) 133/106 0/239 NDk ND NKl NK NK NK NK NK NK NK
  1. aCSF antibodies to B. burgdorferi s.s B31 whole cell antigen.
  2. bCSF antibodies to C6-peptide.
  3. cIntrathecal antibody production index.
  4. dCells/μl, mononuclear cell count.
  5. eOC-bands, oligoclonal bands in CSF.
  6. fDuration of symptoms before first CSF sampling.
  7. gObserved tick bite.
  8. hObserved erythema migrans.
  9. IFP, facial nerve paralysis.
  10. jNA: not applicable.
  11. kND: not done.
  12. lNK: not known.