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Table 1 Baseline characteristics of the untreated and treated LNB patients and of the borrelia antibody negative patients

From: CXCL13 and neopterin concentrations in cerebrospinal fluid of patients with Lyme neuroborreliosis and other diseases that cause neuroinflammation

    

Antibodies

      

Presenting symptom

Group

No

Age, years (Median, range)

Sex (F/M)

B31a(pos/neg)

C6b(pos/neg)

IT-indexc(pos/neg/ND)

Cells/μld(Median, range)

OC-bandse(pos/neg)

Protein (mg/ml) (Median, range)

Duration of symptomsf(days) (Median, range)

Tick biteg(No of patients)

EMh(No of patients)

FPi

Radiculits/Radiating pain

Untreated LNB

38

66 (3–80)

16/22

37/1

37/1

29/3/6

104 (0–1516)

21/4

1034 (454–3148)

30 (0–120)

11

2

19

30

Treated LNB

24

64 (34–79)

8/16

22/2

18/6

19/4/1

35 (0–120)

10/0

601 (267–1597)

NAj

NA

NA

NA

NA

Non-LNB

239

50 (1–91)

133/106

0/239

NDk

ND

NKl

NK

NK

NK

NK

NK

NK

NK

  1. aCSF antibodies to B. burgdorferi s.s B31 whole cell antigen.
  2. bCSF antibodies to C6-peptide.
  3. cIntrathecal antibody production index.
  4. dCells/μl, mononuclear cell count.
  5. eOC-bands, oligoclonal bands in CSF.
  6. fDuration of symptoms before first CSF sampling.
  7. gObserved tick bite.
  8. hObserved erythema migrans.
  9. IFP, facial nerve paralysis.
  10. jNA: not applicable.
  11. kND: not done.
  12. lNK: not known.