Figure 6

IP-10 is induced in astrocytes in response to pro-inflammatory cues. Representative images of cells in mixed glial cultures treated for 24 hours with vehicle (0.1% BSA in PBS), TNFα (50 ng/ml), IL-1β (10 ng/ml) or LPS (10 ng/ml) +/- IFNγ (10 ng/ml) labelled with IP-10 (green), GFAP (red) and Hoechst (blue), scale bar = 100 μm. GFAP, glial fibrillary acidic protein; IP-10, interferon inducible protein-10; LPS, lipopolysaccharide.