| TD | FXS | ||||
---|---|---|---|---|---|---|
Cytokine | LPS | LPS + DHPG | P-value | LPS | LPS + DHPG | P-value |
GM-CSF | 50.4 (27.9 to 58.9) | 39.6 (19.5 to 42.9) | 0.04a | 45.2 (17.7 to 70.7) | 55.3 (20.1 to 107.2) | 0.28 |
IL-1β | 1,245.3 (957.4 to 1,855.5) | 1,567.6 (1,160.2 to 2,235.0) | 0.05a | 1,146.0 (607.9 to 1,748.2) | 2,326.9 (952.6 to 3,313.6) | < 0.01b |
IL-6 | 3,203.9 (2,043.8 to 5,14.0) | 2,856.1 (1,701.6 to 4,715.8) | 0.33 | 2,900.2 (1,792.2 to 5,110.3) | 4,366.9 (2,047.0 to 6,251.1) | 0.21 |
IL-10 | 271.2 (106.3 to 765.6) | 100.0 (85.0 to 515.8) | 0.40 | 286.8 (184.0 to 573.0) | 179.3 (76.3 to 342.1) | 0.01b |
IL-12(p40) | 59.2 (36.9 to 72.5) | 24.1 (16.3 to 51.2) | 0.01a | 25.0 (6.2 to 77.3) | 46.1 (15.1 to 91.0) | 0.37 |
TNFα | 838.4 (626.3 to 1,034.4) | 570.7 (485.1 to 914.5) | 0.03a | 724.2 (413.0 to 1,381.2) | 1,010.4 (458.1 to 1,510.4) | 0.49 |