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Figure 2 | Journal of Neuroinflammation

Figure 2

From: Neutralization of chemokine-like factor 1, a novel C-C chemokine, protects against focal cerebral ischemia by inhibiting neutrophil infiltration via MAPK pathways in rats

Figure 2

Protective effect of anti-CKLF1 on cerebral infarct volume. Bar graph shows effects of anti-CKLF1 antibody on infarct volume at 24 and 72 hours after reperfusion. Anti-CKLF1 antibody (0.1, 0.5 or 1 μg) was injected into the right cerebral ventricle immediately after reperfusion. The white area represents the area of infarction in the brains of ischemic rats and the non-ischemic area is red. Animals treated with anti-CKLF1 antibody showed less cerebral infarction in a dose-dependent manner compared to vehicle. Normal rabbit IgG had no significant effect. Each data point shows the mean ± SEM for six rats. *P < 0.05, **P < 0.01, ***P < 0.001, compared with vehicle group.

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