Figure 7From: Neutralization of chemokine-like factor 1, a novel C-C chemokine, protects against focal cerebral ischemia by inhibiting neutrophil infiltration via MAPK pathways in rats The effect of anti-CKLF1 antibody on mitogen-activated protein kinase (MAPK) signal pathways. Anti-CKLF1 antibody (0.1, 0.5 or 1 μg) was injected into the right cerebral ventricle immediately after reperfusion. MAPK signal proteins were measured in ischemic cortex. Treatment with anti-CKLF1 antibody inhibited the phosphorylation level of p38, ERK and JNK in the rat ischemic cortex. Each data point shows the mean ± SEM for five rats. ## P < 0.01, compared with sham-operated group; *P < 0.05, **P < 0.01, compared with vehicle group.Back to article page