Exposure | Exposure categories | Developmental category | ASD versus GP | DD versus GP | ||||
---|---|---|---|---|---|---|---|---|
 |  | ASD (N = 84) n (%) | DD (N = 49) n (%) | TD (N = 159) n (%) | Crude OR (95% CI) | Adjusted ORa( 95% CI) | Crude OR (95% CI) | Adjusted ORb(95% CI) |
MCP-1 | Q1 | 27 (32.14) | 17 (34.69) | 41 (25.79) | Reference | Reference | Reference | Reference |
Q2 | 13 (15.48) | 14 (28.57) | 39 (24.53) | 0.50 (0.23 – 1.12) | 0.49 (0.20 – 1.20) | 0.86 (0.37 – 1.99) | 0.52 (0.16 – 1.71) | |
Q3 | 15 (17.86) | 9 (18.37) | 39 (24.53) | 0.58 (0.27 – 1.26) | 0.48 (0.20 – 1.14) | 0.55 (0.22 – 1.39) | 0.45 (0.13 – 1.54) | |
Q4 | 29 (34.52) | 9 (18.37) | 40 (25.16) | 1.10 (0.55 – 2.17) | 0.93 (0.43 – 2.01) | 0.54 (0.21 – 1.35) | 0.55 (0.15 – 1.97) | |
≤ 90% | 66 (78.57) | 45 (91.84) | 143 (89.94) | Reference | Reference | Reference | Reference | |
> 90% | 18 (21.43) | 4 (8.16) | 16 (10.06) | 2.43 (1.17 – 5.07) | 3.24 (1.41 – 7.47) | - | - | |
MIP-1α | Q1 | 23 (27.38) | 22 (44.90) | 41 (25.79) | Reference | Reference | Reference | Reference |
Q2 | 20 (23.81) | 7 (14.29) | 39 (24.53) | 0.91 (0.43 – 1.92) | 0.86 (0.36 – 2.02) | 0.33 (0.12 – 0.87) | 0.21 (0.05 – 0.78) | |
Q3 | 19 (22.62) | 13 (26.53) | 42 (26.42) | 0.80 (0.38 – 1.69) | 1.01 (0.37 – 2.70) | 0.57 (0.25 – 1.29) | 0.36 (0.10 – 1.23) | |
Q4 | 22 (26.19) | 7 (14.29) | 37 (23.27) | 1.06 (0.50 – 2.20) | 1.53 (0.52 – 4.49) | 0.35 (0.13 – 0.92) | 0.29 (0.06 – 1.35) | |
>10% | 70 (83.33) | 14 (28.57) | 143 (89.94) | Reference | Reference | Reference | Reference | |
≤ 10% | 14 (16.67) | 35 (71.43) | 16 (10.06) | 1.78 (0.82 – 3.86) | 1.72 (0.71 – 4.14) | 3.57 (1.59 – 8.01) | 3.36 (1.16 – 9.69) c | |
≤ 90% | 70 (83.33) | 46 (93.88) | 140 (88.05) | Reference | Reference | Reference | Reference | |
> 90% | 14 (16.67) | 3 (6.12) | 19 (11.95) | 1.47 (0.69 – 3.11) | 1.76 (0.70 – 4.39) | - | - | |
RANTES | Q1 | 26 (30.95) | 21 (42.86) | 40 (25.16) | Reference | Reference | Reference | Reference |
Q2 | 23 (27.38) | 9 (18.37) | 40 (25.16) | 0.88 (0.43 – 1.80) | 0.82 (0.37 – 1.81) | 0.42 (0.17 – 1.04) | 0.34 (0.10 – 1.15) | |
Q3 | 20 (23.81) | 14 (28.57) | 40 (25.16) | 0.76 (0.37 – 1.59) | 0.63 (0.28 – 1.43) | 0.66 (0.29 – 1.49) | 0.55 (0.19 – 1.58) | |
Q4 | 15 (17.86) | 5 (10.20) | 39 (24.53) | 0.59 (0.27 – 1.28) | 0.46 (0.18 – 1.16) | 0.24 (0.08 – 0.71) | 0.14 (0.03 – 0.62) | |
> 10% | 68 (80.95) | 33 (67.35) | 143 (89.94) | Reference | Reference | Reference | Reference | |
≤ 10% | 16 (19.05) | 16 (32.65) | 16 (10.06) | 2.10 (0.99 – 4.45) | 2.42 (1.05 – 5.55) | 4.33 (1.96 – 9.54) | 3.78 (1.29 – 11.03) | |
≤ 90% | 79 (94.05) | 46 (93.88) | 143 (89.94) | Reference | Reference | Reference | Reference | |
> 90% | 5 (5.95) | 3 (6.12) | 16 (10.06) | 0.56 (0.20 – 1.60) | 0.59 (0.18 – 1.89) | - | - | |
Eotaxin | Q1 | 25 (29.76) | 17 (34.69) | 41 (25.79) | Reference | Reference | Reference | Reference |
Q2 | 23 (27.38) | 9 (18.37) | 37 (23.27) | 1.02 (0.49 – 2.09) | 0.95 (0.42 – 2.14) | 0.58 (0.23 – 1.47) | 0.88 (0.27 – 2.85) | |
Q3 | 19 (22.62) | 12 (24.49) | 42 (26.42) | 0.74 (0.35 – 1.54) | 0.58 (0.25 – 1.32) | 0.68 (0.29 – 1.62) | 0.62 (0.20 – 1.88) | |
Q4 | 17 (20.24) | 11 (22.45) | 39 (24.53) | 0.71 (0.33 – 1.52) | 0.60 (0.20 – 1.79) | 0.68 (0.28 –1.63) | 1.11 (0.27 – 4.58) | |
≤ 90% | 76 (90.48) | 44 (89.80) | 143 (89.94) | Reference | Reference | Reference | Reference | |
> 90% | 8 (9.52) | 5 (10.20) | 16 (10.06) | 0.94 (0.38 – 2.29) | 1.10 (0.36 – 3.34) | 1.01 (0.35 – 2.93) | 1.24 ( 0.34 – 4.42)c | |
IFN-γ | Non-detected | 65 (77.38) | 42 (85.71) | 116 (72.96) | Reference | Reference | Reference | Reference |
Detected | 19 (22.62) | 7 (14.29) | 43 (27.04) | 0.78 (0.42 – 1.46) | 0.91 (0.47 – 1.75) | 0.45 (0.18 – 1.07) | 0.64 (0.23 – 1.76)c | |
IL-1β | Non-detected | 65 (77.38) | 39 (79.59) | 122 (76.73) | Reference | Reference | Reference | Reference |
Detected | 19 (22.62) | 10 (20.41) | 37 (23.27) | 0.96 (0.51 – 1.80) | 1.11(0.52 –2.35) | 0.84 (0.38 – 1.85) | 0.65 (0.19 – 2.23) | |
IL-2 | Non-detected | 57 (67.86) | 41 (83.67) | 110 (69.18) | Reference | Reference | Reference | Reference |
Detected | 27 (32.14) | 8 (16.33) | 49 (30.82) | 1.06 (0.60 – 1.87) | 1.14 (0.38 – 3.43) | 0.43 (0.19 – 1.00) | 0.26 (0.01 – 8.76) | |
IL-4 | Non-detected | 65 (77.38) | 42 (85.71) | 118 (74.21) | Reference | Reference | Reference | Reference |
Detected | 19 (22.62) | 7 (14.29) | 41 (25.79) | 0.84 (0.45 – 1.56) | 0.95 (0.49 – 1.85) | 0.48 (0.20 – 1.15) | 0.64 (0.23 – 1.80)c | |
IL-6 | Non-detected | 65 (77.38) | 39 (79.59 | 119 (74.84) | Reference | Reference | Reference | Â |
Detected | 19 (22.62) | 10 (20.41) | 40 (25.16) | 0.87 (0.46 – 1.62) | 1.01 (0.52 – 1.96) | 0.76 (0.34 – 1.66) | 0.91 (0.35 – 2.35)c | |
IL-10 | Non-detected | 45 (53.57) | 25 (51.02) | 86 (54.09) | Reference | Reference | Reference | Reference |
 | Detected | 39 (46.43) | 24 (48.98) | 73 (45.91) | 1.02 (0.60 – 1.73) | 0.17 (0.02 – 1.55) | 1.13 (0.59 – 2.14) | 1.53 (0.68 – 3.48)c |