Figure 4
From: Interleukin-1 beta guides the migration of cortical neurons
Down-regulation and up-regulation of IL-1R1 by specific siRNAs and h-IL-1R1, respectively. (A) Representative western blots showing the down-regulation and up-regulation of IL-1R1 by specific siRNAs or human IL-1R1 homologue (h-IL-1R1) in cultured cortical neurons, respectively. (B) Histograms represent the average expression of IL-1R1, normalized to the value of the parallel control. Quantitative data are shown as mean ± SEM from three independent experiments. **P <0.01, versus scramble group. (C) Representative western blots showing the rescue efficiency of h-IL-1R1 in cultured HEK 293 cells. RNAi-resistant h-IL-1R1 was co-transfected with IL-1R1-i1 or with CAG-GFP, respectively. (D) Quantitative data are shown as mean ± SEM from three independent experiments. **P <0.01 versus control group. CAG-GFP = pCAG-IRES-EGFP.