Figure 9
From: Glimepiride reduces CD14 expression and cytokine secretion from macrophages
RAW 264 cells digested with PI-PLC are hyporesponsive to lipopolysaccharide (LPS). (A) The concentrations of TNF produced by RAW 264 cells pre-treated with control medium (●), PI-PLC (○) or heat-inactivated PI-PLC (■) and incubated with LPS. Values are means ± SD from triplicate experiments performed 4 times, n = 12. (B) The concentrations of IL-1β produced by RAW 264 cells pre-treated with control medium (●), PI-PLC (○) or heat-inactivated PI-PLC (■) and incubated with LPS. Values are means ± SD from triplicate experiments performed 4 times, n = 12. (C) The concentrations of IL-6 produced by RAW 264 cells pre-treated with control medium (●), PI-PLC (○) or heat-inactivated PI-PLC (■) and incubated with LPS. Values are means ± SD from triplicate experiments performed 4 times, n = 12.