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Figure 2 | Journal of Neuroinflammation

Figure 2

From: Cerebrospinal fluid levels of inflammation, oxidative stress and NAD+are linked to differences in plasma carotenoid concentrations

Figure 2

Association between carotenoids and reduced levels of peripheral and central IL-6. (A) Inverse association between plasma lycopene and plasma IL-6 levels. A significant inverse association exists between plasma lycopene and plasma IL-6 (P = 0.02, R2 = 0.21, n = 34). Comparisons were made using multiple linear regression controlling for age and gender. (B) Inverse association between plasma total carotenoids and plasma IL-6 levels. A significant inverse association exists between total plasma carotenoids and plasma IL-6 (P = 0.01, r = −0.44, n = 34), however this relationship does not remain statistically significant after controlling for age and gender (P = 0.06). Comparisons were made using the Pearson correlation coefficient and multiple linear regression controlling for age and gender. (C) Inverse association between plasma β-cryptoxanthin and cerebrospinal fluid (CSF) IL-6 levels. A significant inverse association exists between plasma β-cryptoxanthin and CSF levels of IL-6 (P = 0.04, R2 = 0.45, n = 36). Comparisons were made using multiple linear regression controlling for age and gender. (D) Inverse association between total carotenoids and CSF IL-6 levels. A significant inverse association exists between plasma total carotenoids and CSF levels of IL-6 (P = 0.01, r = −0.44, n = 36), however this relationship does not remain statistically significant after controlling for age and gender (P = 0.06). Comparisons were made using the Pearson correlation coefficient and multiple linear regression controlling for age and gender.

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