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Figure 1 | Journal of Neuroinflammation

Figure 1

From: Inhibitory effect of ent-Sauchinone on amyloidogenesis via inhibition of STAT3-mediated NF-κB activation in cultured astrocytes and microglial BV-2 cells

Figure 1

Structural interaction between ent -Sauchinone and STAT3. ent-Sauchinone was prepared from 4-(oxiran-2-yl) phenyl acetate, Pd(OAc)2 and tributyl phosphine (A). Pull-down assay identifies an interaction between the ent-Sauchinone and STAT3. ent-Sauchinone was conjugated with cyanogen bromide Epoxy-activated Sepharose 6B (B). Docking model of ent-Sauchinone with STAT3 as described in Materials and Methods (C and D).

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Journal of Neuroinflammation

ISSN: 1742-2094