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Table 1 Participant characteristics

From: Platelet-activating factors are associated with cognitive deficits in depressed coronary artery disease patients: a hypothesis-generating study

Characteristic

All CAD patients (N = 24)

Major depressed subgroup (N = 15)

Associations with Global Cognition (N = 24)

Sociodemographic

Value

Value

(t or r, P value)

Age

60.3 (9.4)

59.6 (9.2)

-0.01, 0.98

Male (%)

70.8

73.3

-0.29, 0.78

Living alone (%)

33.3

40.0

-0.52, 0.61

White (%)

70.8

66.7

1.67, 0.20*

Years of education

14.9 (3.1)

15.3 (3.2)

0.10, 0.63

Vascular risk factors

   

Hypertension (%)

70.8

66.7

-0.21, 0.84

Smoking history (%)

79.2

80.0

0.56, 0.58

Years smoked

27.6 (13.4)

25.3 (13.7)

-0.09, 0.70

Diabetic (%)

41.7

40.0

0.31, 0.76

Body mass index

29.8 (5.4)

28.5 (5.3)

0.11, 0.61

Dyslipidemia (%)

79.2

86.7

0.75, 0.46

Number of vascular risk factors

3.6 (1.5)

3.7 (1.5)

0.23, 0.29

VO2 peak (ml/(kg min))

18.5 (4.7)

19.1 (4.8)

0.17, 0.44

Systolic blood pressure (mm Hg)

121.3 (17.9)

123.9 (16.9)

-0.33, 0.11

Diastolic blood pressure (mm Hg)

74.5 (10.7)

77.3 (12.3)

-0.12, 0.57

Cardiac history

   

Percutaneous transluminal coronary angioplasty (%)

20.8

26.7

0.74, 0.58*

Myocardial infarction or ischaemic heart disease (%)

50.0

46.7

 

Coronary artery bypass graft (%)

29.2

26.7

 

Median weeks since event

14.0

14.0

 

First episode of CAD (%)

70.0

60.0

1.56, 0.13

Psychometric

   

Met criteria for a major depressive episode (%)

62.5

100.0

-0.86, 0.40

History of depression (%)

45.8

53.3

0.59, 0.56

HAM-D score

12.5 (4.8)

14.9 (3.8)

-0.20, 0.35

Concomitant medications (%)

   

Antidepressants

8.3

6.7

0.64, 0.53

Acetylsalicylic acid

75.0

80.0

1.46, 0.16

Platelet inhibitor

66.7

60.0

-1.33, 0.20

Statin

100.0

100.0

-

Anti-inflammatory

4.2

6.7

-

Anti-diabetic agents

37.5

33.3

0.45, 0.66

  1. VO2, volume of oxygen; HAM-D, Hamilton rating scale for depression; t test and Pearson coefficient summarized associations between participant characteristics and global cognitive performance where appropriate. Data summarized using mean (with standard deviation) unless otherwise stated. *One-way analysis of variance (ANOVA) (with F value) performed for global cognition across ethnicity and cardiac history groups, respectively.