Table 1 Quantitative features of IBA1-IR phenotypes in human dACC gray matter
From: Morphometric characterization of microglial phenotypes in human cerebral cortex
Cell body | |||||
|---|---|---|---|---|---|
|  | Area (μm2) | Roundness | Min feret (μm) | Max feret (μm) | Max-min feret (μm) |
Ramified | 30.8 ± 0.9 | 0.8 ± 0.0 | 5.9 ± 0.1 | 6.9 ± 0.1 | 1.0 ± 0.0 |
Range | 26.7 to 36.0 | 0.7 to 0.8 | 5.3 to 6.4 | 6.5 to 7.6 | 0.8 to 1.2 |
Primed | 79.1 ± 9.6 | 0.5 ± 0.0 | 8.1 ± 0.3 | 14.5 ± 1.9 | 6.3 ± 1.7 |
Range | 52.4 to156.9 | 0.2 to 0.7 | 7.0 to 10.0 | 9.3 to 28.6 | 2.3 to18.5 |
Reactive | 68.2 ± 6.1 | 0.4 ± 0.0 | 7.2 ± 0.5 | 14.6 ± 1.1 | 7.3 ± 1.3 |
Range | 31. 8 to 95. 9 | 0.2 to 0.6 | 5.0 to 10.8 | 8.1 to 21.7 | 3.1 to 10.9 |
Amoeboid | 101.0 ± 18.5 | 0.5 ± 0.0 | 9.1 ± 0.6 | 14.6 ±1.5 | 5.4 ± 1.0 |
Range | 41.0 to 225.0 | 0.4 to 0.7 | 6.0 to 13.3 | 9.9 to 27.7 | 3.1 to 14. |
Processes | |||||
|  | Primary processes | Ends | Nodes | Total length (μm) | Volume (μm 3 ) |
Ramified | 5.8 ± 0.5 | 63.6 ± 9.8 | 46 ± 7.7 | 590.6 ± 77.5 | 274.1 ± 31.2 |
Range | 3.0 to 9.0 | 25 to 104.0 | 16.0 to 78.0 | 294.5 to 979.4 | 105.9 to 407.4 |
Primed | 5.5 ± 0.6 | 40.2 ± 7.7 | 28.6 ± 6.5 | 496.0 ± 60.1 | 356.8 ± 67.4 |
Range | 3.0 to 8.0 | 14 to 91.0 | 9.0 to 66.0 | 287.3 to 793.0 | 86.5 to 772.4 |
Reactive | 3.0 ± 0.2 | 9.8 ± 1.8 | 6.1 ± 1.5 | 122.4 ± 18.6 | 102.6 ± 20.8 |
Range | 2.0 to 5.0 | 5.0 to 20.0 | 2.0 to 15.0 | 50.0 to 215.9 | 36.6 to 224.3 |
Amoeboid | 1.2 ± 0.3 | 1.3 ± 0.3 | 0.1 ± 0.1 | 8.5 ± 3.4 | 23.6 ± 15.1 |
Range | 0.0 to 2.0 | 0.0 to 3.0 | 0.0 to 1.0 | 0.0 to 31.2 | 0.0 to 145.9 |