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Table 1 Positron emission tomography imaging agents for neuroinflammation

From: Tracking neuroinflammation in Alzheimer’s disease: the role of positron emission tomography imaging

Process of interest

Biological target

Radiopharmaceutical

Reference

Microglial activation

18-kDa translocator protein

[11C]PK11195

[32]

 

[11C]AC5216

[33]

[11C]PBR2806

[34]

[11C]DPA-713

[35]

[11C] DPA-714

[36]

[11C]MBMP

[37]

[11C]DAC

[38]

[11C]DAA1106

[39]

[11C]vinpocetine

[40]

[18 F]PBR06

[41]

[18 F]FEAC

[42]

[18 F]FEDAC

[42]

[18 F]DAA1106

[43]

Reactive astrocytes

Monoamine oxidase B

[11C]-DED

[30]

[11C]Sch225336

[44]

Phospholipase A2 activity

Metabolism of arachidonic acid

1-[11C]-AA

[31]

[18 F]FAA

[45]