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Figure 2 | Journal of Neuroinflammation

Figure 2

From: Neuronal CCL2 is upregulated during hepatic encephalopathy and contributes to microglia activation and neurological decline

Figure 2

CCL2 levels are elevated following AOM-induced liver failure. (A) CCL2 concentrations in cortex lysates from vehicle and AOM-treated mice, n = 3. (B) CCL2 mRNA expression in the cortex of vehicle- and AOM-treated mice, n = 3. (C) Immunofluorescence for CCL2 (red) and NeuN (green) with DAPI (blue) used as a counterstain in vehicle- and AOM-treated mouse cortices. (D) Quantification of CCL2 immunofluorescence in vehicle- and AOM-treated mouse cortex, n = 3. (E) Serum levels of CCL2 in vehicle- and AOM-treated mice, n = 4. For ELISA, mRNA, and fluorescence quantification analyses * P <0.05 compared to vehicle-treated mice.

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Journal of Neuroinflammation

ISSN: 1742-2094