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Figure 4 | Journal of Neuroinflammation

Figure 4

From: Neuronal CCL2 is upregulated during hepatic encephalopathy and contributes to microglia activation and neurological decline

Figure 4

CCR2 and CCR4 inhibition reduces microglia activation. (A) Cortical IBA1 field fluorescence (red) in vehicle-, AOM-, AOM + INCB-, and AOM + C021-treated mice. (B) Quantification of IBA1 field fluorescence in vehicle-, AOM-, AOM + INCB-, and AOM + C021-treated mice, n = 3. (C) IBA1 immunofluorescence (red) in individual cells in the cortex of vehicle-, AOM-, AOM + INCB-, and AOM + C021-treated mice. For quantitative immunofluorescence analyses * P <0.05 compared to vehicle-treated mice.

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Journal of Neuroinflammation

ISSN: 1742-2094