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Figure 1 | Journal of Neuroinflammation

Figure 1

From: A20 deficiency causes spontaneous neuroinflammation in mice

Figure 1

Baseline A20 mRNA expression in mouse cerebral cortex and hippocampus. (A) A20 and (C) IκBα mRNA levels in cerebral cortex (CX) and hippocampus (HC) of wild type (WT), A20 heterozygous (HT) and A20 knockout (KO) mice, measured by qPCR. Graph shows relative mRNA levels after normalization with mRNA levels of housekeeping gene βactin. Results are expressed as mean ± SEM of three to four animals per genotype. **P < 0.01. ND: not detectable. (B) Western blot (WB) analysis of IκBα expression in CX and HC of A20 WT, HT and KO mice. Immunoblotting for the housekeeping protein βactin was used to control for loading. Results are representative of three animals per genotype.

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