Infarct development in surfactant protein-D (SP-D) knock out (KO) and wild type (WT) mice after permanent middle cerebral artery occlusion (pMCAO). (A) Toluidine blue staining of brain sections from WT and SP-D KO mice 1 and 5 days after pMCAO. (B) Direct estimation of cortical infarct volume showed no difference in infarct volumes between WT and SP-D KO at 1 or 5 days after pMCAO (Student’s t-test; n = 8 to 15). Ctx: cortex, IF: infarct, Str: striatum. Results are expressed as mean ± SD. Scale bar: 1 mm.