Treatment with mepazine attenuates experimental autoimmune encephalomyelitis (EAE) and promotes remission. (A) Clinical scores of mepazine-treated (n = 14) or vehicle-treated (n = 30) mice after treatment starting when mice reach a clinical score of 2.0. Results are obtained from two independent experiments and data are depicted as mean ± SEM. (B) Kaplan-Meier plot showing remission (clinical score ≤1.5) after mepazine treatment from mice in figure A. *P <0.05, ***P <0.001.