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Table 3 Quantification of spinal cord cell infiltration, demyelination and axonal damage

From: Pharmacological inhibition of MALT1 protease activity protects mice in a mouse model of multiple sclerosis

Treatment

Demyelination (%)a

APP+/mm2a

CD3+/mm2a

Mac-3+/mm2a

Vehicle

32.9 ± 6.0

45.4 ± 5.5

114.2 ± 59.2

480.8 ± 191.9

Mepazine

17.6 ± 7.5

29.2 ± 12.9

50.3 ± 22.5

246.5 ± 113.6

  1. Samples were obtained from vehicle (n = 5) or mepazine (n = 6) treated animals. aResults are displayed as mean ± SEM.