From: Pharmacological inhibition of MALT1 protease activity protects mice in a mouse model of multiple sclerosis
Treatment
Demyelination (%)a
APP+/mm2a
CD3+/mm2a
Mac-3+/mm2a
Vehicle
32.9 ± 6.0
45.4 ± 5.5
114.2 ± 59.2
480.8 ± 191.9
Mepazine
17.6 ± 7.5
29.2 ± 12.9
50.3 ± 22.5
246.5 ± 113.6