Figure 5
From: The mTOR kinase inhibitors polarize glioma-activated microglia to express a M1 phenotype
Effects of mammalian target of rapamycin (mTOR) inhibitors on cell viability. (A) C6 glioma cells were administrated with mTOR inhibitors. Microglia cells were treated for 48 h with control-conditioned medium (C-CM) (B) or CM from glioma cells activated with lipopolysaccharide (LPS)/IFNγ (LI-CM) (C) and mTOR inhibitors. Effects on cell viability were assessed by the MTS reduction assay. Data were analyzed by one-way analysis of variance followed by Bonferroni post hoc test. ***P <0.001, versus Control, °°°P <0.001 versus C-CM or LI-CM.