Interferon regulatory factor (IRF) 3 is critical for the development of experimental autoimmune encephalomyelitis

Table 1 Incidence of actively induced experimental autoimmune encephalomyelitis in wild-type and irf3 ^−/− mice ^a

^aWild-type and interferon regulatory factor 3–knockout (irf3 ^−/−) mice were immunised with myelin oligodendrocyte glycoprotein (MOG_35–55) in Complete Freund’s adjuvant, and Bordetella pertussis toxin was administered on day 0 and day 2. Mice were scored daily for clinical signs of experimental autoimmune encephalomyelitis. Data represent disease incidence in each group in five independent experiments.

ISSN: 1742-2094