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Figure 3 | Journal of Neuroinflammation

Figure 3

From: Complex pattern of interaction between in uterohypoxia-ischemia and intra-amniotic inflammation disrupts brain development and motor function

Figure 3

Myelin basic protein expression is decreased on postnatal day 15 following prenatal transient systemic hypoxia-ischemia and/or lipopolysaccharide injury. (A) At postnatal day 15 no difference in lateral ventricle volume is observed (n = 3-6). (B,C) Similarly, stereological investigations reveal ionized calcium-binding adapter molecule 1 (Iba1) + and glial fibrillary acidic protein (GFAP) + load in the fimbria are not significantly different following the different types of prenatal insults (n = 3-4). (D) Myelin basic protein immunolabeling shows reduced protein expression in the periventricular white matter of transient systemic hypoxia-ischemia (TSHI) and TSHI + lipopolysaccharide (LPS) pups compared to shams. Scale bar = 100 μm.

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Journal of Neuroinflammation

ISSN: 1742-2094