Figure 3

CpG-treated neutropenic animals that survived the infection showed a delay in the clearance of bacteria. Bacterial concentrations in (A) cerebellum and (B) spleen were determined 14 days after intracerebral E. coli K1 infection in those animals which survived the infection (n = 10-20 mice/group). Horizontal bars indicate median values. Statistical analysis was performed by Mann-Whitney U test.