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Figure 4 | Journal of Neuroinflammation

Figure 4

From: Experimental mouse model of optic neuritis with inflammatory demyelination produced by passive transfer of neuromyelitis optica-immunoglobulin G

Figure 4

Inflammation in optic nerve lesions. (A) Immunostaining for albumin, ionized calcium-binding adaptor molecule-1 (Iba1); microglia and CD45 (leukocytes) in the optic nerve after 3-days continuous perichiasmal infusion of neuromyelitis optica immunoglobulin G antibody (NMO-IgG) and complement. (B) (Left) Immunostaining with markers for macrophages, neutrophils and eosinophils. (Right) Number of infiltrating cells of each per 0.01 mm2 (mean ± SEM, n = 3).

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