Table 2 IPA annotation of molecular and cellular functions for the action of EGCG in LPS-stimulated BV-2 cells
Name | P value | # Molecules | Molecules |
|---|---|---|---|
Free radical scavenging | 1.56E-09 – 1.38E-02 | 9 | ACTB, ALDH2, ANXA1, HMOX1, PRDX1, PRDX2, PRDX3, SOD1, SOD2 |
Post-translational modification | 9.96E-09 – 1.01E-02 | 15 | ACADL, ALDH2, ERP29, GLUD1, HMOX1, HPRT1, HSPA5, HSPA8, HSPD1, IMPDH2, LRPAP1, P4HB, SOD1, SOD2, TCP1 |
Protein folding | 9.96E-09 – 3.37E-03 | 7 | ERP29, HSPA5, HSPA8, HSPD1, LRPAP1, P4HB, TCP1 |
Nucleic acid metabolism | 1.78E-07 – 1.67E-02 | 17 | ALDH2, ATIC, ATP5A1, CMPK2, HMOX1, HPRT1, HSPA5, HSPA8, HSPD1, IMPDH2, MTAP, PKM, RUVBL1, SOD1, SOD2, TALDO1, UMPS |
Small molecule biochemistry | 4.34E-07 – 1.67E-02 | 34 | ACADL, AKR1A1, ALDH2, ANXA1, ATIC, ATP5A1, CMPK2, DLD, FABP5, GLUD1, GNPDA1, GSTO1, HMOX1, HPRT1, HSPA5, HSPA8, HSPD1, IMPDH2, LGALS1, MTAP, MVD, P4HB, PDIA3, PHGDH, PKM, PRDX1, PRDX2, PRDX3, RUVBL1, SOD1, SOD2, TALDO1, TIMM50, UMPS |