Figure 8

Expression of CD80 and CD86 as MFI in B cells of HAM/TSP patients and HCs following in vitro treatment with IFN-α and IFN-β. (A,B) IFN-β but not IFN-α enhanced expression of CD86 in B cells in both (A) HCs (**p = 0.0070, n = 10) and (B) HAM/TSP patients, (*p = 0.023, n = 8). (*p < 0.05, **p < 0.01, ***p < 0.001; ANOVA with Bonferroni’s multiple comparison post test).