Figure 2

CX3CR1 deficiency attenuates neuronal apoptosis after middle cerebral artery occlusion. (A) Double staining with cleaved Caspase 3 (red) and NeuN (green) antibodies in peri-infarct area of wild-type (WT) and CX3CR1^-/- mice 72 hours after middle cerebral artery occlusion. (B) Quantification of Cleaved-Caspase 3/NeuN positive cells. CX3CR1^-/- mice have fewer Cleaved-Caspase 3⁺NeuN⁺ cells in the peri-infarct zone. **P < 0.01 by Student’s t-test. n = 4 per group. Scale bars = 50 μm.