Figure 5From: Translocator protein (18 kDa) (TSPO) is expressed in reactive retinal microglia and modulates microglial inflammation and phagocytosis The TSPO ligand XBD173 promotes microglial filopodia formation. (A-D) Representative images of phalloidin-stained murine BV-2 microglial cells treated with 50 μM XBD173 in the absence or presence of 50 ng/ml LPS. (E-H) Representative images of phalloidin-stained human iPS-derived microglia (iPSdM) treated with 30 μM XBD173 in the absence or presence of 250 ng/ml LPS. LPS, lipopolysaccharide; TSPO, translocator protein (18 kDa).Back to article page