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Figure 4 | Journal of Neuroinflammation

Figure 4

From: Knockout of CXCR5 increases the population of immature neural cells and decreases proliferation in the hippocampal dentate gyrus

Figure 4

CXCR5 -/- is associated with increased baseline locomotor activity and decreased anxiety-like behaviour but not anhedonia-like behaviour. (A) CXCR5-/- is associated with increased locomotor activity over 5 min in the open field test as compared to WT controls (* P <0.0001; n = 11 per group). (B) CXCR5-/- is associated with increased time spent in the inner zone of the open field test as compared to WT controls (* P = 0.015; n = 11 per group). (C) No difference in saccharin preference between CXCR5-/- and WT animals (P = 0.098; n = 11 per group).

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