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Figure 2 | Journal of Neuroinflammation

Figure 2

From: Chronic stress enhances microglia activation and exacerbates death of nigral dopaminergic neurons under conditions of inflammation

Figure 2

Validation of the stress model. (A) Body weight gain (in grams). *P < 0.05. (B) Adrenal gland weight (in milligrams; bars) and ratio between adrenal gland weight and body weight gain (scatterplot and line). **P < 0.01, # P < 0.01 (for adrenal gland weight/body weight gain ratio). (C) Serum corticosterone (percentage of control animals). *P < 0.01 compared with control, a P < 0.01 compared with previous time point (S1d to S10d indicates days subjected to variate stress). Statistical significance was calculated by using Student’s t-test to compare data before (C) and after 10 days (S10d) of variate stress. Data were derived from one-way analysis of variance followed by the least significant difference (LSD) post hoc test for multiple range comparisons.

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