Figure 6From: Chronic stress enhances microglia activation and exacerbates death of nigral dopaminergic neurons under conditions of inflammation Effect of stress and lipopolysaccharide on inhibitor of nuclear factor κB kinase, subunit β, and Iba-1 in the substantia nigra. Iba-1 immunofluorescence (A), (D) and (G) and inhibitor of nuclear factor κB kinase, subunit β (IKKβ), immunofluorescence (B), (E) and (H) show robust induction of IKKβ in Iba-1-labelled microglial cells in the merged images (C), (F) and (I). Images (A), (B) and (C) were taken of an animal injected with lipopolysaccharide (LPS; L). Images (D) through (F) were taken of a stressed animal injected with LPS (SL). Images (G), (H) and (I) are high-magnification photomicrographs showing one representative cell. Scale bars: (A) through (F), 200 μm; (G) through (I), 25 μm. Arrows indicate colocalizing cells.Back to article page