Figure 4From: NFκB-mediated CXCL1 production in spinal cord astrocytes contributes to the maintenance of bone cancer pain in mice RM-1 cell inoculation induces GFAP upregulation in the spinal cord. (A-D) GFAP-IR was mild in naïve mice (A), but increased at 7 days (B), 14 days (C), and 21 days (D) in inoculated mice. (E) Statistical analysis shows increased GFAP intensity after RM-1 cell inoculation. **P <0.01, ***P <0.001 vs. sham. n = 4 mice per group.Back to article page