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Figure 1 | Journal of Neuroinflammation

Figure 1

From: Activation of brain indoleamine 2,3-dioxygenase contributes to epilepsy-associated depressive-like behavior in rats with chronic temporal lobe epilepsy

Figure 1

Study designs. (A) Study design 1: chronic temporal lobe epilepsy induces depressive behavior. (B) Study design 2: 1-methyltryptophan inhibits indoleamine 2,3-dioxygenase 1 directly. (C) Study design 3: minocycline inhibits indoleamine 2,3-dioxygenase 1 indirectly.1-MT, 1-methyltryptophan; 5-HT, serotonin; FST, forced swim test; IDO, indoleamine 2,3-dioxygenase; KYN, kynurenine; SE, status epilepticus; TPT, taste preference test; TRY, tryptophan.

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Journal of Neuroinflammation

ISSN: 1742-2094