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Figure 6 | Journal of Neuroinflammation

Figure 6

From: Paroxetine ameliorates lipopolysaccharide-induced microglia activation via differential regulation of MAPK signaling

Figure 6

Paroxetine relieves microglia-mediated neurotoxicity. BV2 cells were first treated with lipopolysaccharide (LPS) (100 ng/mL) for 24 hours with or without 30 minutes of paroxetine pretreatment at 5 μM. The media were then collected as condition media and added to SH-SY5Y cells. After 24 hours incubation, cell viability of SH-SY5Y was assessed and expressed as percentage of the control, which was set as 100%. *P < 0.05. Values are means ± SE of three independent experiments. PAR, paroxetine; LPS, lipopolysaccharide.

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