Figure 3

Cytokine expression profile in antigen presenting cells from the central nervous system of mice with experimental autoimmune encephalomyelitis. Expression of IL-1β, IL-6, IL-12p35, IL-23p19, and transforming growth factor (TGF)β in fluorescence-activated cell sorted antigen presenting cells (CD11c⁺ microglia, CD11c⁻ microglia and CD45^high CD11c⁺) from the central nervous system was analyzed by quantitative real-time PCR. Data are presented as means ± SEM of three individual experiments (n ≥ 5). ns, Not significant; *P < 0.05; **P < 0.01. ND, not detected.