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Figure 3 | Journal of Neuroinflammation

Figure 3

From: Ganglioside deficiency causes inflammation and neurodegeneration via the activation of complement system in the spinal cord

Figure 3

Expression levels of complement components were upregulated in the spinal cord and liver of wild-type (WT) and double knockout (DKO) mice. mRNA levels of complement genes (C1qα, C1qβ, C1qγ, C2, C3, C4, C5, C6, C7, C8α, C8β, C8γ, C9, C3aR, and C5aR) in the spinal cord (A) and liver (B) of WT and DKO mice were analyzed by real-time reverse transcription-polymerase chain reaction (RT-PCR) and presented after correction with the mouse GAPDH gene. The numbers of mice examined were as follows: 28-week-old male WT (n = 3; open columns) and DKO (n = 3; closed columns); data were presented as mean ± standard deviation (SD) and were analyzed by Student t test (*P <0.05; **P <0.01). ND, not detected.

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