Table 1 Functional properties of differentially expressed target genes
From: Peripheral inflammation is associated with remote global gene expression changes in the brain
| Gene symbol | Gene name |
|---|---|
| Interferon-stimulated genes | |
| Ctsc | Cathepsin C |
| Gbp2 | Guanylate-binding protein 2 |
| Gbp3 | Guanylate-binding protein 3 |
| Gbp6 | Guanylate-binding protein 6 |
| Gbp7 | Guanylate-binding protein 7 |
| Ifit1 | Interferon-induced protein with tetratricopeptide repeats |
| Ifitm3 | Interferon-induced transmembrane protein |
| Irgm1 | Immunity-related GTPase, family M, member 1 |
| Lgals3bp | Lectin, galactoside-binding, soluble, 3 binding protein |
| Oasl2 | 2′-5′ Oligoadenylate synthetase-like 2 |
| Rnf213 | Ring finger protein 213 |
| Rtp4 | Receptor transporter protein 4 |
| Sp100 | Nuclear antigen Sp100 |
| Stat1 | Signal transducer and activator of transcription 1 |
| Acute phase reactants | |
| Lcn2 | Lipocalin 2 |
| Saa3 | Serum amyloid A3 |
| Serpina3n | Serine (or cysteine) peptidase inhibitor, clade A |
| Immunity system components | |
| C4b |C4a | Complement component 4B (Childo blood group) | complement 4A (Rodgers blood group) |
| Fcgr4 | Fc receptor, IgG, low affinity IV |
| H2-K1 | Histocompatibility 2, K1, K region |
| Pglyrp1 | Peptidoglycan recognition protein 1 |
| Cell surface molecules | |
| Il2rg | Interleukin 2 receptor, gamma chain |
| Ly6a | Lymphocyte antigen 6 complex, locus A |
| mRNA editing | |
| Apobec3 | Apolipoprotein B mRNA editing enzyme |
