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Figure 2 | Journal of Neuroinflammation

Figure 2

From: Toll-like 4 receptor inhibitor TAK-242 decreases neuroinflammation in rat brain frontal cortex after stress

Figure 2

Toll-like receptor-4 immunoreactivity in the brain frontal cortex of rats in control and stress conditions. Sections (30 μm) through the frontal cortext of rats in (A, C, E) control and (B, D, F) stress conditions. The respective cellular markers appear in green: neurons are identified with NeuN (A, B), microglia with IBA-1 (C, D) and astroglia with glial fibrillary acidic protein (E, F). In all cases toll-like receptor (TLR)-4 is marked in red. TLR-4 localizes to the respective cellular marker with some areas of overlap appearing yellow/orange in the merged image (white arrows in A-F). Scale bars: 20 μm.

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