Figure 8

Antioxidant effects of systemic TAK-242 after stress exposure in rat brain frontal cortex. (A) MDA and (B) 4-hydroxynonenal (4-HNE) protein adduct levels in frontal cortex homogenates of control (CONTROL) and stressed rats with TAK-242 (S(TAK)) or without TAK-242 (STRESS). Data represent the mean ± SEM (n = 5 per group). One-way analysis of variance followed by Newman–Keuls post hoc test. *P < 0.05 versus control. ^# P < 0.05 versus stress. O.D., optical density.